What is Plasma Donation Type Uses and Side Effects Plasma Therapy in Corona-virus

What is Plasma Donation Type Uses and Side Effects Plasma Therapy in Corona-virus-human blood-red-cells-Image

Overview:

You must have heard of plasma, it is the most important element in the human body. This is an in-depth article about what is plasma, Plasma donation and its types, the procedure of plasma donation, history of plasma, Plasma therapy, and all the side effects of plasma therapy.

What is Plasma?

Plasma is light yellow viscous and fluid in the blood. Which is 55% volume of the blood we have in our body. The remaining 45 % have blood cells in the body.
90% part of the plasma is containing water and the rest 10% of plasma in the blood is having protein, organic and inorganic elements.

Just to understand better what the plasma is or in? In other words, we can say that if we remove WBC, RBC, Platelets, and other cellular components from our blood then the remaining liquid will be called plasma in the blood.

What is plasma Donation? and The Power of Plasma Donation:

Many patients with rare and genetic disorders are relying on you. That is because blood contains plasma which is a key ingredient in treatments they need to survive.

And the only source or the only way to get plasma is from the healthy plasma donors only.

As mentioned earlier that plasma is protein-rich, gold, or yellow-colored liquid portion of blood.

It all starts when a donor visits one of the more than 700 source plasma donation centers in North America and Europe.

Procedure for Plasma Donation:

What is Plasma Donation Type Uses and Side Effects Plasma Therapy in Corona-virus-Plasma Donations-Image

1. The Plasma donors will check in at reception presenting a government-issued ID with current address proof.
2. The donor of plasma then takes a few minutes to complete a health history questionnaire.
3. They must pass a health screening prior to each donation before being able to donate their plasma.
4. Source plasma donors in the United States and some European Countries are given some modest compensation for their time and travel.
5. Plasma which is used to make lifesaving plasma protein therapies is collected through a process knows as plasmapheresis.
6. During this process, an automated device is used to separate the plasma from the blood of the human body.
7. Red blood cells and other components are returned to the main donor once the plasma is collected from him.
8. After when the plasma is collected from the donor, it is tested for suitability for further manufacture, frozen, and then held for at least 60 days prior to pooling.
9. It has to pass these rigorous steps to be pooled with other plasma donations.
10. Before the process of protein, the extraction begins each plasma pool is further tested. 
11. During this process, the lifesaving protein is extracted from the plasma. 
12. Later on, the separated specific protein are purified and adjusted for optimal dosage before becoming the finished therapeutic product.
13. Each source plasma donation tracked the entire time from the donation to all the way to therapy.
14. The most important thing is that only healthy people should donate plasma because every year it takes approximately 130 plasma to treat one person with a primary immune deficiency. 900 donations to treat one person with Alpha-1 antitrypsin deficiency and 1200 donations to treat one person with hemophilia.

Plasma Donation is the process to save lives and it all starts with you. We must say thank you to all the plasma donors that donate the plasma.

To learn more and to find the nearest plasma donation center. you can visit www.donatingplasma.org 

Do You Know? 

Plasma makes a difference by saving and improving the lives of people with rare, genetic, and chronic diseases.

States of Matter:-

There are all 18 states of matter, rather than 3 states of matter which are Solid, Liquid, and Gas.

History of Plasma:

Plasma was discovered by Sir William Crookes as the fourth state of matter but gave the name as Radiant Matter, not Plasma.

Later on an English Physicist J.J Thomson stated that this fourth state of matter is a state in which atoms, molecules are not there but electrons and ions move freely in this state just because of which plasma can produce of generating electricity.

Then later in 1928 Irving Langmuir, a scientist gave this the name of Plasma.

Plasma as the State of Matter:

Plasma state of matter is nothing but just a state where electrons and other ions move freely like it happens in gas. Also in a plasma state of matter, there are not molecules and there are no atoms in this state of plasma which is the fourth state of plasma.

Uses Of Artificial Plasma:

We use plasma or plasma technology in our daily life like the given examples below;

1. Plasma is used in fluorescent bulbs, lamps, or tube lights we use in our houses as energy savers, there is gas in it or we can say plasma is present in these electronics.
2. Neon Signs are also an best example of using plasma in it.
3. Plasma is also used in cleaning and sterilization of food because of plasma's destroying power fungus and bacteria and food get sterilized.
4. Apart from all of these examples the Monitors and the LED we are using for better picture quality are one of the most common and famous examples using Plasma technology or using plasma.

Types of Plasma:

There are two types of plasma present in the universe.

• Natural Plasma

          Sun and shinning stars and luminous clouds are the examples of Natural Plasma.

• Artificial Plasma

          LED's, Bulbs, Tube-lights are examples of artificial plasma.

What is Plasma Therapy:

What is Plasma Donation Type Uses and Side Effects Plasma Therapy in Corona-virus-Plasma therapy-Image

Plasma therapy is used to improve immunity of a patient who is suffering from any kind of disease. Taking the example of a Novel Corona Virus or COVID-19.

Nowadays coronavirus become the worst disease in the world. Plasma therapy is being used for patients who are suffering from COVID-19 or coronavirus.

Simple Definition of Plasma Therapy:

In this therapy, the patients who have been recovered from the disease donates plasma for those patients whose immunity is not much stronger than the patient who has recovered from the disease.

With the help of this therapy, plasma helps the patient to fight with the virus but it can not destroy the virus in any case.

The donor who is donating their plasma can only donate their plasma after 4 weeks of recovery from the disease.

Also according to the guidelines of WHO plasma therapy can not be used at everyone who is sick.

 

Side Effects of Plasma: by (Dr. Rupal MBBS - DCH MCGP MGPA(GB))

In a case where plasma therapy is helping to improve the sick conditions of the patients on the other side, plasma therapy is showing some serious side effects

Before getting any plasma related therapy or treatment you must be aware of the side effects that plasma therapy shows.

What is Plasma Donation Type Uses and Side Effects Plasma Therapy in Corona-virus-side-effects-Image

Side Effects:

1. First side effect of plasma therapy is Allergy or Citrate Toxicity(CT).
2. The second side effect it can do to you is transfusion-related acute lung injury(TRALI).
3. Because of the respiratory failure patient, it can cause patient death.
4. Transfusion-associated circulatory overload (TACO) can be an issue.
5. Anaphylactic Shock or Reactions can be seen.
6. Also, It can cause you any kind of serious infections in the body.
7. The sixth side effect of plasma therapy is HYPERFIBRINOLYSIS.
8. On number Seven  because of plasma therapy it can result in ENHANCED INFECTION - COVID-19.
9. The next side effect of Plasma therapy is it can cause you suppression of the immune system (SIS).
10. Graft Versus Host Disease(GVHD).

According to the research of the "Mayo Clinic Research Report", they are saying that till now they have not found something just because of which this plasma therapy can be used on COVID-19 or coronavirus infected patients.

According to the research of the "Mayo Clinic Research Report", they are saying that till now they have not found something just because of which this plasma therapy can be used on COVID-19 or coronavirus infected patients.